Methods of treating gastrointestinal diseases and disorders
AssigneeCristcot LLC
InventorJennifer J. Davagian
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Abstract
Formulations comprising hydrocortisone are disclosed in a suppository for methods of treating ulcerative colitis and other gastrointestinal diseases and disorders. Administering a single hydrocortisone suppository once a day achieves remission or reduction of a symptom, optionally followed by a period of time in which the dosage is reduced.
Claims31
-24. (canceled)
A method for treating ulcerative colitis comprising rectally administering once a day a single suppository to a patient in need thereof comprising about 80 mg to about 180 mg of hydrocortisone base or a salt thereof for a period of time sufficient to achieve remission or reduction of a symptom and followed by a period of administering a reduced dosage, wherein no more than one suppository comprising hydrocortisone base or a salt thereof is administered to the patient in a single day.
A method of achieving clinical remission in a patient suffering from ulcerative colitis, comprising rectally administering to a patient in need thereof once a day a single suppository comprising about 80 mg to about 180 mg of hydrocortisone base or a salt thereof to a patient in need thereof, wherein no more than one suppository comprising hydrocortisone base or a salt thereof is administered to the patient in a single day.
A method for treating ulcerative colitis comprising rectally administering once a day in the morning a single suppository comprising greater than about 80 mg to about 180 mg of hydrocortisone base or a salt thereof for a period of time sufficient to achieve remission or reduction of a symptom, wherein no more than one suppository comprising hydrocortisone base or a salt thereof is administered to the patient in a single day.
Dependencies are inferred from the claim text.