Universal multi-detection system for microplates with confocal imaging

A device for analyzing one or more samples, the device comprising:

• a receptacle support configured to support a microplate comprising a microplate well configured to hold a sample;
• a confocal imaging subsystem configured to image the sample on a cell level;
• a non-imaging analyzing subsystem configured to analyze the sample on a well level, the non-imaging analyzing subsystem configured to provide at least one of a first measurement modality to measure an absorbance of the sample, a second measurement modality to measure fluorescence of the sample, and a third measurement modality to measure chemiluminescence of the sample.