Dnazyme for eosinophil peroxidase and uses thereof
AssigneeMcMaster University
InventorsMonsur Ali, Manali Mukherjee, Alfredo Capretta, Parameswaran Nair, John Brennan
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Abstract
This disclosure relates to catalytic nucleic acids, catalytic nucleic acid probes, biosensors, lateral flow devices, and kits for detecting the presence or absence of eosinophil peroxidase. Also provided are methods for detecting the presence or absence of eosinophil peroxidase in a test sample, using the catalytic nucleic acids, catalytic nucleic acid probes, biosensors, lateral flow devices, and kits.
Claims28
A catalytic nucleic acid for detecting eosinophil peroxidase comprising a nucleic acid sequence selected from the group consisting of SEQ ID NOs:
- 10, 12, 14, 16, 24, 25, 27-29, 33-40, 42, 43, 48, 49, 51-53, 57-64, 66, 67, 70, 71, 76, 80, and 81, a functional fragment thereof, or a functional variant thereof.
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9-11. (canceled)
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22-24. (canceled)
28-29. (canceled)
32-33. (canceled)
Dependencies are inferred from the claim text.