Cultivation method for enhancing differentiation efficiency and functionality of nk cells
AssigneeMaru Therapeutics Co., Ltd.
InventorsKyung-Sun KANG, Daekee KWON, Bo Kyung MOON
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AssigneeMaru Therapeutics Co., Ltd.
InventorsKyung-Sun KANG, Daekee KWON, Bo Kyung MOON
Estimating the term…
Provided is a cultivation method for enhancing the differentiation efficiency and functionality of NK cells, based on the finding that the differentiation efficiency of NK cells is increased by selecting and differentiating cells exhibiting specific characteristics, wherein the efficiency of NK cell differentiation from induced pluripotent stem cells was enhanced by altering conditions at specific stages of the process of differentiating induced pluripotent cells into NK cells, conditions for the composition of stage-specific media used, and the treatment methods for the composition, and in the light of acquiring functional NK cells as well as such quantitative increase, the method can be advantageously used for qualitative improvement.
A method of differentiating NK cells from stem cells, the method comprising selecting allophycocyanin (APC)-expressing hematopoietic progenitor cells from among hematopoietic progenitor cells cultured from stem cells.
A method of differentiating NK cells from stem cells, the method comprising:
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