Marker and method for detecting inflammation-related diseases
AssigneeBeijing Mdtk Biotechnology Co., Ltd.
InventorsJianxia Wang, Jun LI, Ying Liu, Haoxiang Kang, Sufang Mao, Yu Cao
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Abstract
The present application relates to a marker and a method for detecting inflammation-related diseases. The marker of the present application can stably exist in an ex vivo body fluid sample and does not gather on a cell membrane, so the detection result is very accurate. The marker can be widely applied to the medical detection of inflammation-related diseases, having good clinical application prospects.
Claims20
A monoclonal antibody #50 or an antigen-binding fragment thereof, characterized by comprising antigen complementarity determining regions of a heavy chain variable region, CDR1, CDR2, and CDR3, and antigen complementarity determining regions of a light chain variable region, CDR1, CDR2, and CDR3;
- the amino acid sequences of wherein the antigen complementarity determining regions CDR1, CDR2, and CDR3 of wherein the heavy chain variable region are SEQ ID NO:
- 6:
- GYTFTNYW, SEQ ID NO:
- 7:
- TKPSNGDI, and SEQ ID NO:
- 8:
- AVGYY respectively;
- the amino acid sequences of wherein the antigen complementarity determining regions CDR1, CDR2, and CDR3 of wherein the light chain variable region are SEQ ID NO:
- 9:
- QSLLNSGNQKNY, WAY, and SEQ ID NO:10:
- QNDYSYPLT respectively.
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Dependencies are inferred from the claim text.