Catalysts and methods of use thereof
AssigneeYale University
InventorsMingjiang Zhong, Xiaowei Zhang
Life of this patent
Estimating the term…
Abstract
The present disclosure relates, in part, to catalyst compounds and methods of use thereof for stereocontrolled living radical polymerization. In another aspect, the present disclosure relates to isotactic polymers and/or polymers having controlled tacticity, and applications thereof. In certain embodiments, the isotactic polymers and/or controlled tacticity polymers are prepared according to the methods of the present disclosure.
Claims33
A compound selected from the group consisting of:
- or a salt, solvate, stereoisomer, or isotopologue thereof, wherein:
- M, if present, is Co;
- Z is absent or an anionic ligand;
- R1, if present, is
- R2a, R2b, and R2c, if present, are each independently selected from the group consisting of H, optionally substituted C1-C6 alkyl, optionally substituted C3-C8 cycloalkyl, optionally substituted C6-C10 aryl and optionally substituted C2-C10 heteroaryl;
- R3a, R3b, R3c, R3d, R3e, R3f, R3g, and R3h, if present, are each independently selected from the group consisting of H and optionally substituted C1-C6 alkyl;
- L1, if present, is selected from the group consisting of -(optionally substituted C6-C10 arylenyl)-* and -(optionally substituted C2-C10 heteroarylenyl)-*,
- wherein a substituent of the C6-C10 arylenyl or the C2-C10 heteroarylenyl in L1 can combine with a substituent of the C6-C10 aryl or C2-C10 heteroaryl in R2b to form an optionally substituted C20-C30 heterocycloalkenyl;
- L2, if present, is selected from the group consisting of *—C(═O)N(R5)(optionally substituted C1-C6 alkylenyl)-, *—C(═O)O(optionally substituted C1-C6 alkylenyl)-, *—C(═O)(optionally substituted C1-C6 alkylenyl)-, *-(optionally substituted C1-C6 alkylenyl)-, *—N(R5)C(═O)(optionally substituted C1-C6 alkylenyl)-, *—OC(═O)(optionally substituted C1-C6 alkylenyl)-, *—C(═O)N(R5)(optionally substituted C1-C6 heteroalkylenyl)-, *—C(═O)O(optionally substituted C1-C6 heteroalkylenyl)-, *—C(═O)(optionally substituted C1-C6 heteroalkylenyl)-, *-(optionally substituted C1-C6 heteroalkylenyl)-, *—N(R5)C(═O)(optionally substituted C1-C6 heteroalkylenyl)-, and *—OC(═O)(optionally substituted C1-C6 heteroalkylenyl)-;
- R4 is an optionally substituted C6-C8 heterocycloalkyl,
- wherein the C6-C8 heterocycloalkyl comprises at least three atoms selected from the group consisting of N, O, and S;
- and
- each occurrence of R5, if present, is independently selected from the group consisting of H, optionally substituted C1-C6 alkyl, optionally substituted C3-C8 cycloalkyl, optionally substituted C2-C10 heterocyclyl, and optionally substituted C6-C10 aryl.
3-5. (canceled)
7-9. (canceled)
11-14. (canceled)
16-17. (canceled)
21-27. (canceled)
(canceled)
33-34. (canceled)
36-38. (canceled)
A polymer composition of Formula (III):
- wherein:
- each occurrence of A comprises o units of
- each occurrence of T1 is selected from the group consisting of C(═O)OR13, optionally substituted alkyl, and halogen;
- T2 is selected from the group consisting of H,
- o is an integer ranging from 1 to 10;
- each occurrence of p is an integer ranging from 1 to 5,000;
- R12 is substituted with at least one substituent comprising a heteroatom having at least one coordinating lone pair of electrons,
- wherein the R12 in each unit of
- is identical;
- and
- each occurrence of R13 is selected from the group consisting of H, optionally substituted C1-C6 alkyl, optionally substituted C3-C8 cycloalkyl, optionally substituted C2-C10 heterocyclyl, and optionally substituted C6-C10 aryl.
(canceled)
43-46. (canceled)
(canceled)
(canceled)
(canceled)
Dependencies are inferred from the claim text.