Pharmaceutical composition
AssigneeMexichem Fluor S.A. De C.V.
InventorsStuart CORR, Timothy James Noakes
Life of this patent
Estimating the term…
Abstract
A pharmaceutical composition comprises a drug component. The drug component is a combination of one pharmaceutically acceptable salt of glycopyrrolate, beclomethasone dipropionate, and one long acting beta-2-agonist (LABA) selected from formoterol and pharmaceutically acceptable salts thereof. The pharmaceutical composition also comprises a propellant component. The propellant component is at least 90 weight percent 1,1-difluoroethane (HFA-152a). The pharmaceutical composition is in the form of a solution and optionally comprises ethanol, but is free of other polar solvents/co-solvents. The drug component is the sole drug component in the pharmaceutical composition.
Claims30
A pharmaceutical composition comprising:
- (i) a drug component that is a combination of one pharmaceutically acceptable salt of glycopyrrolate, beclomethasone dipropionate, and one long acting beta-2-agonist (LABA) selected from formoterol and pharmaceutically acceptable salts thereof;
- and
- (ii) a propellant component, wherein the propellant component is at least 90 weight percent 1,1-difluoroethane (HFA-152a);
- wherein the pharmaceutical composition is in the form of a solution and optionally comprises ethanol, but is free of other polar solvents/co-solvents;
- and
- the drug component is the sole drug component in the pharmaceutical composition.
A pharmaceutical composition consisting of:
- (i) a drug component that is a combination of one pharmaceutically acceptable salt of glycopyrrolate, beclomethasone dipropionate, and one long acting beta-2-agonist (LABA) selected from formoterol and pharmaceutically acceptable salts thereof;
- (ii) a propellant component, wherein the propellant component is at least 90 weight percent 1,1-difluoroethane (HFA-152a);
- and
- (iii) optionally one or more of ethanol, water, and an acid stabilizer selected from an inorganic acid;
- wherein the pharmaceutical composition is in the form of a solution.
Dependencies are inferred from the claim text.