Gamma-aminobutyric acid derivative comprising polycyclic structure, method for preparing same, and use thereof

A compound of general formula I, a chiral isomer thereof or a pharmaceutically acceptable salt thereof,

• wherein
• R1 and R2 are independently selected from H, halogen, and C1-C6 alkyl;
• each of R3, R4, R5 and R6 is independently selected from H, halogen, C1-C6 alkyl, and C1-C6 alkoxy;
• or R3 and R4 together with a C atom to which they are connected form C3-C6 cycloalkyl, or R5 and R6 together with a C atom to which they are connected form C3-C6 cycloalkyl;
• each of R7, R8, R9 and R10 is independently selected from H, halogen, and C1-C6 alkyl;
• m and n are independently selected from 0, 1, 2, and 3;
• alternatively, when n≥1, a C atom connected to R8 and an adjacent C atom connected to R10 are capable of forming C3-C6 cycloalkyl together with R8 and R10;
• when n≥1, a solid line and a dashed line between the C atom connected to R8 and the adjacent C atom connected to R10 represent that a chemical bond between the C atom connected to R8 and the C atom connected to R10 can be a single bond or a double bond;
• and when the chemical bond represents the double bond, corresponding R7 and R9 are absent.