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AssigneeSociete des Produits Nestle S.A.
InventorsUmberto DE MARCHI, Astrid HORSTMAN, Jerome FEIGE
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Composition comprising a combination of oleuropein or metabolite thereof and taurine or functional derivative thereof are provided. The composition may be an oral nutritional composition, for example a nutritional supplement, an oral nutritional supplement, a food product, a food for special medical purpose (FSMP). The composition can be administered to an individual in need thereof for improving a physiological state linked to metabolic fatigue in one or more cells, (ii) increasing mitochondrial energy and mitochondrial calcium uptake in one or more cells, and (iii) increasing antioxidant capacity, reducing oxidative stress and/or enhancing mitochondrial function, (iv) treating or preventing a calcium deficiency/depletion disorder in an individual. Additionally or alternatively, the method can treat or prevent a mitochondria-related disease or a condition associated with altered mitochondrial function in an individual in need thereof or at risk thereof.
A method for in (i) improving a physiological state linked to metabolic fatigue in one or more cells, (ii) increasing mitochondrial energy and mitochondrial calcium uptake in one or more cells, and (iii) increasing antioxidant capacity, reducing oxidative stress and/or enhancing mitochondrial function, (iv) treating or preventing a calcium deficiency/depletion disorder in an individual, the method comprising administering an effective amount of a composition comprising a combination of oleuropein and/or a metabolite thereof and taurine and/or a functional derivative thereof to the individual.
A method of for treating, reducing an incidence of, and/or reducing a severity of a mitochondria-related disease or a condition associated with altered mitochondrial function in an individual in need thereof or at risk thereof, the method comprising orally administering an effective amount of a composition comprising a combination of oleuropein and/or a metabolite thereof and taurine and/or a functional derivative thereof to the individual in need thereof or at risk thereof.
A method for delaying off-set of metabolic decline, maintaining muscle mass and/or muscle function, decreasing oxidative stress, maintaining immune function and/or maintaining cognitive function in a healthy older adult, the method comprising administering an effective amount of a composition comprising a combination of oleuropein and/or a metabolite thereof and taurine and/or a functional derivative thereof to the healthy older adult.
A method for enhancing at least one of mental performance or muscle performance in an individual, the method comprising administering an effective amount of a composition comprising a combination of oleuropein and/or a metabolite thereof and taurine and/or a functional derivative thereof to the individual.
A method for improving or maintaining cognitive function in an individual, the method comprising administering an effective amount of a composition comprising a combination of oleuropein and/or a metabolite thereof and taurine and/or a functional derivative thereof to the individual.
A unit dosage form comprising a combination of a combination of oleuropein and/or a metabolite thereof and taurine and/or a functional derivative thereof in an amount effective for at least one of i) treating, reducing an incidence of, or reducing a severity of a mitochondria-related disease or condition associated with altered mitochondrial function (ii) improving in a physiological state linked to metabolic fatigue in one or more cells, (iii) increasing mitochondrial energy and mitochondrial calcium uptake in one or more cells, and (iv) treating or preventing a calcium deficiency/depletion disorder. (v) increasing metabolic rate, (vi) improving or maintaining cognitive function, or (vii) increasing or maintaining mitochondrial function.
A kit comprising a combination of oleuropein and/or a metabolite thereof and taurine and/or a functional derivative thereof in one or more containers.
Dependencies are inferred from the claim text.