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US 2026/0167990 A1Published application
Recombinant aav vectors useful for reducing immunity against transgene products
AssigneeUniversity of Massachusetts
InventorsGuangping Gao, Phillip D. Zamore, Shaoyong Li
Life of this patent
Estimating the term…
Abstract
The disclosure in some aspects, relates to nucleic acids, compositions and kits useful for gene therapy with reduced immune response to transgene products.
Claims22
1-19. (canceled)
A recombinant Adeno-Associated Virus (rAAV) comprising a transgene encoding an RNA transcript that comprises binding sites for at least two immune-associated miRNAs.
40-63. (canceled)
Dependencies are inferred from the claim text.