Automated brachytherapy treatment planning using knowledge-based dose estimations

A system, comprising:

• at least one processor;
• and
• at least one memory including program instructions which when executed by the at least one processor causes operations comprising:
• providing at least one anatomical mask and an applicator mask as inputs to a neural network;
• generating, by the neural network based on the at least one anatomical mask and the applicator mask, one or more dwell positions or one or more corresponding dwell times for a radioactive source within an applicator to deliver a radiation treatment to a patient;
• providing the one or more dwell positions or the one or more corresponding dwell times as inputs to a brachytherapy delivery unit;
• and
• delivering, by the brachytherapy delivery unit, the radiation treatment to the patient by causing the radioactive source to travel through the applicator to the one or more dwell positions while pausing at each dwell position for a corresponding dwell time of the one or more corresponding dwell times.

A non-transitory computer readable medium storing instructions, which when executed by at least one data processor, cause operations comprising:

• providing at least one anatomical mask and an applicator mask as inputs to a neural network;
• generating, by the neural network, a dose prediction based on the at least one anatomical mask and the applicator mask;
• converting the dose prediction into one or more dwell positions and one or more corresponding dwell times for a radioactive source within an applicator to deliver a radiation treatment to a patient;
• and
• delivering the radiation treatment to the patient based on the one or more dwell positions and the one or more corresponding dwell times.