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AssigneesTaiwan Puritic Corp., China Medical University
InventorsLei Wan, Hui-Ju Lin, Yu-An Hsu, Chi-Fong Lin
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A Lactiplantibacillus plantarum subsp. plantarum strain, and a bacterial membrane vesicles derived from Lactiplantibacillus plantarum subsp. plantarum strain, and uses of the same for improvement of eye diseases are provided. The Lactiplantibacillus plantarum subsp. plantarum strain EP21 and the bacterial membrane vesicles are derived from Lactiplantibacillus plantarum subsp. plantarum strain EP21. Both the Lactiplantibacillus plantarum subsp. plantarum strain EP21 and the bacterial membrane vesicles derived from Lactiplantibacillus plantarum subsp. plantarum strain EP21 can inhibit inflammation by suppressing inflammatory factors and improve eye diseases effectively.
A Lactiplantibacillus plantarum subsp. plantarum strain EP21 with an accession number of BCRC (Biosource Collection and Research Center (BCRC)) 911210 for use in improvement of eye diseases, wherein the strain includes a segment of sequence shown in Seq ID No. 3.
The composition as claimed in claim 11, wherein a vesicle diameter of the MV is ranging from 100 nm to 300 nm.
Dependencies are inferred from the claim text.