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AssigneesHiroshima University, Rohto Pharmaceutical Co., Ltd.
InventorsMasayuki SHIMADA, Takashi UMEHARA, Noriyasu ISHIKAWA, Takashi TAKIJIRI
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The purpose of the present invention is to provide an excellent infertility treatment with which it is possible to increase the implantation rate of an embryo (fertilized egg) by improving the uterine environment. The present invention is a uterine treatment composition containing a mesenchymal stem cell culture supernatant, and is used as a uterine environment-improving agent, an implantation aid, an embryo transplant liquid, a sperm transplantation liquid, or an implantation rate-improving agent. The mesenchymal stem cells are preferably derived from adipose tissue, umbilical cord tissue, or bone marrow tissue.
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A method for improving uterine environment, comprising treating a uterus with a composition comprising mesenchymal stem cell culture supernatant.
A method for aiding implantation of a fertilized ova, comprising treating a uterus with a composition comprising mesenchymal stem cell culture supernatant.
A method for an embryo transfer, comprising treating embryos (fertilized ova) with a composition comprising mesenchymal stem cell culture supernatant.
A method for an artificial insemination, comprising treating sperm with a composition comprising mesenchymal stem cell culture supernatant.
A method for improving an implantation rate of a fertilized ova, comprising treating a uterus, sperm, or embryo (fertilized ova) with a composition comprising mesenchymal stem cell culture supernatant.
Dependencies are inferred from the claim text.