Treprostinil formulations and their uses

An inhalation formulation comprising iloprost or a pharmaceutically acceptable salt thereof, treprostinil or a pharmaceutically acceptable salt thereof, and benzalkonium chloride, wherein the concentration of iloprost ranges from about 10 μg/mL to about 500 μg/mL, and wherein the concentration of treprostinil ranges from about 200 μg/mL to about 4000 μg/mL.

A method of treating a cardiopulmonary disorder comprising administering by inhalation to a patient in need thereof a therapeutically effective single event dose of an inhalation formulation comprising a preservative and treprostinil or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier, wherein the treprostinil is at a concentration of about 100 mg/mL to about 25 mg/mL, and wherein the formulation is in a solution form.