Systems and methods for the production of human polyclonal antibodies
AssigneeSab, LLC
InventorsJay HOOPER, Eddie SULLIVAN, Hua WU
Life of this patent
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Abstract
Disclosed herein is a method for producing human antibodies against a pathogen comprising injecting a non-human animal with a pathogen-derived DNA vaccine in at least two locations of the animal; injecting the animal with an adjuvant in a location of the animal different from the location of the DNA vaccine location; collecting plasma from the animal after the injections; and purifying polyclonal antibody from the plasma.
Claims20
A method for producing human antibodies against a pathogen comprising:
- a) injecting a non-human animal with a pathogen-derived DNA vaccine in at least two locations of the animal;
- b) injecting the animal with an adjuvant in a location of the animal different from the location of the DNA vaccine location;
- c) collecting plasma from the animal after the injections;
- and
- d) purifying polyclonal antibody from the plasma.
A human polyclonal antibody against a pathogen, produced by:
- a) injecting a non-human animal with a pathogen-derived DNA vaccine in at least two locations of the animal;
- b) injecting the animal with an adjuvant in a location of the animal different from the location of the DNA vaccine location;
- c) collecting plasma from the animal after the injections;
- and
- d) purifying polyclonal antibody from the plasma.
A method for producing human antibodies against a pathogen comprising:
- a) injecting a non-human animal with a pathogen-derived DNA vaccine in at least one location of the animal;
- b) injecting the animal with an adjuvant in a location of the animal different from the location of the DNA vaccine location;
- c) collecting plasma from the animal after the injections;
- and
- d) purifying polyclonal antibody from the plasma.
Dependencies are inferred from the claim text.