Androgen receptor degraders for the treatment of castration-resistant prostate cancer and use thereof

A compound of Formula (I), pharmaceutically acceptable salt, diastereomers, enantiomers, racemates, tautomers, prodrugs, hydrates, or solvates thereof:

• in formula (I),
• wherein Ra and Rb are independently H or —O—CH2-R1,
• R1 is C6-C9 aryl optionally substituted with one or more halos,
• X is —O—CH2-CH(OH)—CH2-NH— or —CH2-NH—;
• Y is —(CH2CH2-O)n1-, —(CH2)n2-O—, n1 and n2 are independently an integer of 1 to 6;
• W is —(CH2)n3-NH—C(═O)—, —(CH2)n4-NH—C(═O)—(CH2)n5-O—, —CH2-CH2-O—, —CH2-C(═O)—, n3, n4 and n5 are independently an integer of 1 to 7;
• and
• Z is