Light box system for optical assay interrogation

A light box for imaging a diagnostic test device, the light box comprising:

• a box structure, the box structure configured to unfold from a shipping configuration to an imaging configuration for use with the diagnostic test device, the box structure comprising:
• a plurality of side walls and an upper surface defining an interior volume;
• and
• at least one aperture in the upper surface configured to allow a mobile device to image the diagnostic test device through the aperture while the diagnostic test device is disposed within the interior volume.

A method of imaging a test device, comprising:

• unfolding a light box from a shipping configuration to an imaging configuration, wherein the light box comprises an aperture;
• placing a test device within the light box in the imaging configuration;
• and
• imaging, using a mobile device, the test device.