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AssigneeHelix Nanotechnologies Inc
InventorsHannu Rajaniemi, Nikolai Eroshenko, Marianna Keaveney, Rachel Smith, Everett Webster, Taylor Gill, Kemo Jammeh, Nikhil Dhar, Kyle Backman, Dario De Jessus Davila Pasillas, Justin Sean Huang, Katherine Rowe, Arianna Lizeth Lopez Sauceda, Nikolai Paul Radzinski, Tao Qin
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Disclosed herein are polynucleotides encoding one or more ruminal-associated antigens, and polypeptides encoded by said polynucleotides. Also provided herein are compositions comprising the same, and method of making and using said compositions.
An isolated polynucleotide encoding one or more ruminal-associated antigens, fragments thereof, variants thereof or variant fragments thereof.
The isolated polynucleotide of any one of the preceding claims, wherein the one or more ruminal antigens are derived from a polypeptide that is involved in attachment to fermenting bacteria, or a fragment or variant or variant fragment thereof.
The isolated polynucleotide of any one of the preceding claims, wherein the one or more ruminal antigens and/or the one or more methanogen antigens are situated on different polynucleotides.
The isolated polynucleotide of any one of the preceding claims, wherein the polynucleotide comprises a signal peptide or a variant or fragment thereof.
The isolated polynucleotide of any one of the preceding claims, wherein the polynucleotide comprises:
The isolated polynucleotide of any one of the preceding claims, wherein the polynucleotide comprises a transmembrane domain.
The isolated polynucleotide of any one of the preceding claims, further comprising a complement C3d-binding polypeptide from an immunoglobulin-binding protein (Sbi) of Staphylococcus aureus.
The isolated polynucleotide of any one of the preceding claims, wherein the polynucleotide is or comprises DNA.
A polypeptide encoded by the polynucleotide of any one of the preceding claims.
Dependencies are inferred from the claim text.