Devices and methods for delivery of multi-component fluids
AssigneeTYBR Health, Inc.
InventorsPeter Alexander SMITH, Timothy J. KEANE, Jr.
Life of this patent
Estimating the term…
Abstract
Provided herein are devices and methods for mixing and delivering a multi-component fluid capable of decreasing post-surgical adhesions. The devices are configured to impart shear stress on the multi-component fluid and increase yield stress of a resulting gel. In some cases, the devices can be airless. In some cases, the devices can use gases to impart additional shear stress on the fluids in the devices. Mixers for imparting sheet stress can include mixer stages, vortex inducers, spacers, or any combination thereof.
Claims35
A device for delivery of a multi-component fluid, the device comprising:
- a housing having a first lumen and a second lumen, wherein the first lumen is configured to receive a first component of the multi-component fluid, and the second lumen is configured to receive a second component of the multi-component fluid;
- a mixer comprising one or more mixer stages and one or more vortex inducers, wherein a proximal end of the mixer is in fluid communication with the first and second lumens, wherein the proximal end is configured to receive the first component and the second component within the mixer and to mix the first component and the second component to form the multi-component fluid;
- and
- a nozzle coupled to the mixer, wherein the nozzle comprises a nozzle outlet configured to receive the multi-component fluid from the mixer and deliver the multi-component fluid from the nozzle outlet.
A method of delivering a multi-component fluid for treatment of a wound, the method comprising:
- a) delivering a first component to a first lumen and a second component to a second lumen of a delivery device, wherein the delivery device comprises:
- (i) a housing having a first lumen and a second lumen, wherein the first lumen is configured to receive a first component of the multi-component fluid, and the second lumen is configured to receive a second component of the multi-component fluid;
- (ii) a mixer comprising one or more mixer stages and one or more vortex inducers, wherein a proximal end of the mixer is in fluid communication with the first and second lumens, wherein the proximal end is configured to receive the first component and the second component within the mixer and to mix the first component and the second component to form the multi-component fluid;
- (iii) a nozzle coupled to the mixer, wherein the nozzle comprises a nozzle outlet configured to receive the multi-component fluid from the mixer and deliver the multi-component fluid from the nozzle outlet;
- and
- (iv) an actuator coupled to the housing;
- b) activating the actuator so that the mixer receives the first component and the second component;
- c) further activating the actuator so that the first component and the second component mix to form the multi-component fluid;
- and
- d) further activating the actuator so that the multi-component fluid is delivered from the nozzle outlet onto a patient's wound.
(canceled)
A method for delivering a multi-component fluid, the method comprising:
- a) delivering a first component and a second component of the multi-component fluid through a first lumen and a second lumen, respectively, of a delivery device, wherein the delivery device comprises:
- (i) a housing having a first lumen and a second lumen, wherein the first lumen is configured to receive a first component of the multi-component fluid, and the second lumen is configured to receive a second component of the multi-component fluid;
- (ii) a mixer comprising one or more mixer stages and one or more vortex inducers, wherein a proximal end of the mixer is in fluid communication with the first and second lumens, wherein the proximal end is configured to receive the first component and the second component within the mixer and to mix the first component and the second component to form the multi-component fluid;
- and
- (iii) a nozzle coupled to the mixer, wherein the nozzle comprises a nozzle outlet configured to receive the multi-component fluid from the mixer and deliver the multi-component fluid from the nozzle outlet;
- b) delivering the multi-component fluid through one or more vortex inducers in the mixer;
- and
- c) delivering the multi-component fluid through the nozzle outlet.
(canceled)
(canceled)
Dependencies are inferred from the claim text.