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US 2026/0153424 A1Published application
Systems and methods for isolating particles in solution by particle permittivity
AssigneeSigil Biosciences, Inc.
InventorsIryna CLARK, Rajaram KRISHNAN
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Abstract
Provided herein are systems and methods of electrohydrodynamic isolation of one or more particles of varying size and dielectric properties.
Claims21
1-120. (canceled)
A method of isolating particles, the method comprising:
- providing a device comprising at least one chip, the at least one chip comprising at least one electrode and at least one substrate, the at least one electrode and the at least one substrate being configured to produce an electric field on or around the substrate when a current is applied to the at least one electrode;
- providing a fluid composition comprising one or more particles;
- modifying a particle permittivity or a membrane permittivity of the one or more particles by applying the electric field;
- and
- isolating the one or more particles based on the particle permittivity or membrane permittivity.
2 more elements
A method of isolating particles, the method comprising:
- providing a fluid composition comprising one or more particles, each having a membrane on a surface of the one or more particles;
- modifying a membrane permittivity of the one or more particles by attaching to, coating, or introducing into the membrane at least one modifier;
- providing a device comprising at least one chip, the at least one chip comprising at least one electrode and at least one substrate, the at least one electrode and the at least one substrate being configured to produce an electric field on or around the substrate when a current is applied to the at least one electrode;
- introducing the fluid composition into the device;
- and
- isolating the one or more particles based on the membrane permittivity of the one or more particles.
3 more elements
Dependencies are inferred from the claim text.