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US 2026/0152467 A1Published application
Dispersing and wetting agents and compositions and methods of use thereof
AssigneeMojave Bio, Inc.
InventorEric STIMPSON
Life of this patent
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Abstract
Aspects of the disclosure include compositions, reaction mixtures, and methods of use thereof, for preventing or reversing aggregation of molecular entities prone to aggregation.
Claims29
A compound having the following structure:
- wherein:
- A is a six-membered aryl or a six-membered heteroaryl, wherein heteroaryl comprises one to three heteroatoms selected from the group consisting of N, O, S, and combinations thereof;
- Y is, individually in each instance, C═O or SO2;
- wherein R1 and R2 are each, individually in each instance, C1-6alkyl or [PEG]p—RA;
- RA is H or C1-6alkyl;
- subscript m is an integer of 1 to 3;
- and
- subscript p is an integer of 1 to 10.
5 more elements
-4. (canceled)
A polymer comprising a saturated hydrocarbon substituted with at least one or more substituents,
- wherein each substituent, individually in each instance is:
- (a) selected from the group consisting of aryl;
- alkyl-aryl;
- aryl-alkyl;
- heteroalkyl-aryl;
- aryl-heteroalkyl;
- heteroaryl;
- alkyl-heteroaryl;
- heteroaryl-alkyl;
- heteroalkyl-heteroaryl;
- heteroaryl-heteroalkyl;
- and combinations thereof;
- and
- (b) non-ionic at 6≤pH≤8;
- (c) optionally substituted with 1 to 6 substituents selected from the group consisting of polyethylene glycol (PEG), —OH, —SH, —NO2, —NO3, —C(O)OH, —NH3, —CH3, —CH2—OH, —CH2—CH2—OH, ═O, and —CN, wherein the optional substituents are not further substituted;
- wherein the polymer:
- (c) is water soluble;
- and
- (d) is transparent to 350 nm to 800 nm wavelength light.
16 more elements
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-46. (canceled)
Dependencies are inferred from the claim text.