Microreactor array platform

A method for sealing a reagent in microreactors of an array of microreactors, the method comprising:

• (a) providing a microreactor array platform;
• (b) injecting the reagent into the microreactor array using the injector;
• and
• (c) directing, using the applicator, a sealing liquid against the first surface of the sealing film to achieve a contact of at least a portion of the second surface with the upper surface of the substrate,
• wherein the microreactor array platform comprises:
• a base having a wall defining a cavity in the base and a reagent inlet port;
• a substrate positioned within the cavity, the substrate having a flat upper surface;
• a sealing film positioned above the substrate and having a first surface and an opposite second surface having a closer proximity to the substrate than the first surface, wherein the sealing film defines an array of microreactors on the second surface and is configured to movably seal the array of microreactors against the upper surface of the substrate;
• the sealing film and the substrate defining a reagent gap providing a fluid path between the microreactor array and the substrate when the second surface of the sealing film is in spaced relationship with the upper surface of the substrate;
• an injector for delivering a reagent into the reagent gap through the reagent inlet port;
• and
• an applicator for directing a sealing liquid against the first surface of the sealing film through a sealing liquid inlet port positioned above the sealing film,
• wherein the sealing film is impervious to fluids, providing a separation between the reagent and the sealing liquid.