Method for drying fecal microbiota multilayer dripping pills
AssigneeShenzhen Wanhe Pharmaceutical Co., Ltd.
InventorsZhongsun WANG, Yang JIN, Baisheng KE, Weijia HUANG, Jun MA
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AssigneeShenzhen Wanhe Pharmaceutical Co., Ltd.
InventorsZhongsun WANG, Yang JIN, Baisheng KE, Weijia HUANG, Jun MA
Estimating the term…
A method for drying fecal microbiota multilayer dripping pills is disclosed. The drying method includes: performing centrifugal deoiling on fecal microbiota multilayer dripping pills by using a deoiling agent, and then performing separation treatment to obtain deoiled dripping pills, wherein the deoiling agent is a mixture of fumed silica, soybean fiber, and oat cellulose; performing blast drying on the deoiled dripping pills to obtain pre-dried dripping pills; and performing negative pressure drying on the pre-dried dripping pills to obtain Huanglong dripping pills. In the drying method provided by the present application, centrifugal deoiling, blast drying, and negative pressure drying are sequentially performed, thereby further reducing the water activity of the Huanglong dripping pills. The data of examples show that the obtained Huanglong dripping pills have a water activity aw of 0.08 to 0.14, exhibit excellent tolerability, particularly in vitro simulated gastrointestinal tolerability, and also exhibit excellent stability.
A method for drying fecal microbiota multilayer dripping pills, wherein the method comprises the steps of:
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