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US 2026/0146996 A1Published application
Examination method for immune-related adverse event enteritis
AssigneesKyoto University, Kinki University
InventorsMasahiro SHIOKAWA, Masataka YOKODE, Takeshi KUWADA, Yuya MURAMOTO, Hisato KAWAKAMI, Kazuhiko NAKAGAWA
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Abstract
Provided is an examination method for irAE enteritis, said examination method comprising a detection step for detecting, as an indicator of ulcerous colitis-like irAE enteritis, an antibody that immunologically reacts with a fragment of, or the entirety of, integrin ανβ6 in a specimen.
Claims16
A method of testing for irAE enteritis, the method comprising:
- detecting an antibody that immunologically reacts with a fragment or an entirety of integrin ανβ6 in a sample as an indicator of ulcerative colitis-like irAE enteritis.
A kit for testing for irAE enteritis, comprising a fragment or an entirety of integrin ανβ6.
A method of testing for irAE enteritis, the method comprising:
- detecting an antibody that immunologically reacts with a fragment or an entirety of integrin ανβ6 in a sample as an indicator of enteritis for which discontinuation of an ICI is recommended.
Dependencies are inferred from the claim text.