Semi-quantitative lateral flow device and method for detecting biomarkers in unprocessed saliva
AssigneeSparked Inc.
InventorsStephanie Buryk-Iggers, Michael Glogauer, Patrick Lawler, Morteza Jeyhani
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Abstract
Provided herein are sensitive lateral flow devices (LFDs) configured for use in an assay to measure the levels of a cardiometabolic disease risk biomarker in a sample from a subject, such as a saliva sample. Also provided herein are methods of using the LFDs disclosed herein in assays for measuring the level of a cardiometabolic disease risk biomarker in a sample from a subject, such as a saliva sample. Further provided herein are methods of manufacturing the LFDs disclosed herein.
Claims20
A semi-quantitative lateral flow device for measuring a cardiometabolic biomarker level in a saliva sample from a subject comprising:
- I) a running liquid zone;
- II) a sample pad zone configured to receive the sample;
- III) a detection zone;
- and
- IV) an absorption zone;
- wherein the running liquid zone, the sample pad zone, the detection zone, and the absorption zone are coupled sequentially by a continuous flow channel, and wherein the detection zone comprises at least one test dot configured to detect the cardiometabolic biomarker in saliva and at least one control dot.
Dependencies are inferred from the claim text.