Recombinant protein comprising protein derived from foot-and-mouth disease virus type o capsid protein and sfc protein and use thereof
AssigneeThe Industry & Academic Cooperation in Chungnam National University (IAC)
InventorHyun-Jin SHIN
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Abstract
The present disclosure relates to a recombinant protein comprising a food and mouth disease virus (FMDV) virus like particle (VLP) and a fragment crystallizable region (Fc) of a swine-derived immunoglobulin linked to the surface of the VLP, and a vaccine composition comprising the recombinant protein. The recombinant protein of the present disclosure may form a self-assembling structure including a virus-like particle using a protein derived from a capsid protein of FMDV, which is an antigenic protein, and a swine Fc protein located on the surface of the virus-like particle, and by using a vaccine composition including the recombinant protein, a specific antibody against FMDV may be effectively produced.
Claims10
A recombinant protein comprising a P12A protein derived from a foot and mouth disease virus (FMDV) capsid and a fragment crystallizable (Fc) region of a swine-derived immunoglobulin.
Dependencies are inferred from the claim text.