Benzothia(di)azepine compounds and their use as bile acid modulators
AssigneeAlbireo AB
InventorsPer-Göran Gillberg, Ingemar Starke, Santosh S. Kulkarni
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Abstract
The invention relates to 1,5-benzothiazepine and 1,2,5-benzothiadiazepine derivatives of formula (I). These compounds are bile acid modulators having apical sodium-dependent bile acid transporter (ASBT) and/or liver bile acid transport (LBAT) inhibitory activity. The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the treatment of cardiovascular diseases, fatty acid metabolism and glucose utilization disorders, gastrointestinal diseases and liver diseases.
Claims7
1-15. (canceled)
A compound, wherein the compound is:
A compound, wherein the compound is:
A compound, wherein the compound is:
Dependencies are inferred from the claim text.