# US 2026/0144992 A1 · Means and methods for using non-excitatory electrical heart failure therapy as a therapy for heart failure with preserved ejection fraction

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 2026/0144992 A1
- Document ID: US20260144992A1
- Status: Published application
- Kind: A1
- Application number: 19/455,907
- Filed: 2026-01-22
- Published: 2026-05-28
- Earliest claimed: 2021-07-02
- Assignees: Impulse Dynamics NV
- Applicants: Impulse Dynamics NV
- Inventors: David PRUTCHI; Simeon Ioannis KEDIKOGLOU; Tamir BEN DAVID
- Web page: https://patentgrep.com/patent/US20260144992A1

## CPC

- A61N 1/3628: {using sub-threshold or non-excitatory signals}
- A61N 1/36507: {controlled by gradient or slope of the heart potential}
- A61N 1/36521: {the parameter being derived from measurement of an electrical impedance}
- A61N 1/36535: {controlled by body position or posture}
- A61N 1/36564: {controlled by blood pressure}
- A61N 1/36571: {controlled by blood flow rate, e.g. blood velocity or cardiac output}
- A61N 1/36578: {controlled by mechanical motion of the heart wall, e.g. measured by an accelerometer or microphone}
- A61N 1/0573: {chacterised by means penetrating the heart tissue, e.g. helix needle or hook}
- A61N 1/37247: {User interfaces, e.g. input or presentation means}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

The present invention relates to non-excitatory electrical heart failure therapy as a therapy for Heart failure with preserved ejection fraction.

## Claims

### Claim 1

A method of treating a patient with non-excitatory electrical heart failure therapy, the method comprising:
a. identifying a patient that suffers of heart failure (HF) and presents pulmonary capillary wedge pressure indexed to cardiac output (PCWP/CO) slope greater than 2 mm Hg/L/min;
b. providing an effective amount of non-excitatory electrical heart failure therapy.