Compositions and methods for treating acromegaly

A method of treating acromegaly, comprising administering to a patient in need thereof a lipid composition comprising 20 mg of octreotide or a pharmaceutically acceptable salt thereof, wherein the lipid composition is administered to the patient once every 28+/−7 days (once every 4 weeks+/−1 week), and wherein the lipid composition contains about 20 mg octreotide base/mL, about 6.5% w/w anhydrous ethanol, about 6.5% w/w propylene glycol, about 0.01% w/w ethylenediaminetetraacetic acid (EDTA), about 0.01% w/w ethanolamine, and soybean phosphatidylcholine/glycerol dioleate in a weight ratio of about 50/50 to final volume.