Antifungal diferulic acid formulation containing poacic acid and poacidiene, method for production, and method of using same
AssigneeWisconsin Alumni Research Foundation
InventorsJohn Ralph, Fachuang Lu, Mehdi Kabbage
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Abstract
A method to produce a mixture comprising poacic acid (X) and poacidiene (Y) and the resulting product-by-process. The method includes the steps of subjecting a solution of ferulic acid to a free-radical coupling reaction to yield an intermediate mixture comprising ferulic acid dehydrodimers and decarboxylating the intermediate mixture to yield a product mixture containing poacic acid (X) and poacidiene (Y).
Claims21
A method to produce a mixture comprising poacic acid and poacidiene from ferulic acid, the method comprising:
- a. subjecting a solution of ferulic acid to a free-radical coupling reaction to yield an intermediate mixture comprising ferulic acid dehydrodimers;
- and
- b. decarboxylating the intermediate mixture of step (a) to yield a product mixture comprising poacic acid and poacidiene.
A method to produce a mixture comprising poacic acid and poacidiene from ferulic acid, the method comprising:
- a. subjecting an aqueous ferulic acid solution to a free-radical coupling reaction to yield an intermediate mixture comprising ferulic acid dehydrodimers;
- and
- b. decarboxylating the intermediate mixture of step (a) to yield a product mixture comprising poacic acid and poacidiene.
A mixture comprising, in combination, poacic acid and poacidiene, made by a method comprising:
- a. subjecting a solution of ferulic acid to a free-radical coupling reaction to yield an intermediate mixture comprising ferulic acid dehydrodimers;
- and
- b. decarboxylating the intermediate mixture of step (a) to yield a product mixture comprising poacic acid and poacidiene.
Dependencies are inferred from the claim text.