Colorimetric detection of a viral infection
AssigneeRamot at Tel-Aviv University Ltd.
InventorsFernando PATOLSKY, Ella BORBERG
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Abstract
Methods, compositions, systems, matrices, and kits for determining a presence, type and/or amount of a viral biomarker in a sample by contacting the sample with one or more agents that selectively reacts with the biomarker and with a colorimetric indicator that exhibits a colorimetric change as a result of a reaction between the agent and a viral biomarker, are provided.
Claims20
A method of determining a presence and/or amount of a viral biomarker in a sample, the method comprising:
- contacting the sample with an agent that selectively reacts with the viral biomarker and with a colorimetric indicator,
- wherein said agent that selectively reacts with the viral biomarker and said colorimetric indicator are selected such that a reaction of said agent with the viral biomarker results in a colorimetric change in said colorimetric indicator, said colorimetric change being indicative of the presence and/or amount of the viral biomarker in the sample,
- wherein said reaction of said agent with the viral biomarker results in a pH change and wherein said colorimetric indicator is a pH indicator.
A kit comprising an agent that selectively reacts with a viral biomarker, and a colorimetric indicator which is such that exhibits a colorimetric change as a result of a reaction between said agent and said viral biomarker,
- wherein said reaction between said agent and said viral biomarker results in a pH change.
A composition comprising a colorimetric indicator which is or comprises a solid matrix and an agent that selectively reacts with a viral biomarker associated with the solid matrix, wherein said reaction of said agent with said viral biomarker results in a pH change and wherein said colorimetric indicator is a pH indicator.
Dependencies are inferred from the claim text.