Cyclic peptide as inhibitors of free-living amoeba
AssigneePurdue Research Foundation
InventorsElizabeth Ivy Parkinson, Gabriela Coy, Chenyang Lu, Samantha Nelson, Christopher Aaron Rice
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Abstract
Cyclic peptides that are inhibitors of a pathogenic free-living amoeba (e.g., Balamuthia mandrillaris, Naegleria fowleri, and Acanthamoeba castellanii), compositions comprising the same, and their use for inhibiting infections or diseases caused by the pathogenic free-living amoeba.
Claims7
A cyclic peptide therapeutic agent selected from:
- or a variant thereof.
A method of inhibiting an infection or a disease caused by a pathogenic free-living amoeba in a patient in need thereof, which method comprises administering an inhibitory effective amount of a cyclic peptide therapeutic agent selected from
- or a variant thereof or a pharmaceutical composition comprising the same, whereupon the infection or disease caused by the pathogenic free-living amoeba in the patient is inhibited.
Dependencies are inferred from the claim text.