US 2026/0139002 A1Published application

Purification of polypeptides

AssigneeAdonis Health Inc.

InventorsDarr R. Kadlubowski, Cyrille V. Gineste

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Purification of a peptide is described herein.

Dependent claims

A method for purifying a polypeptide comprising:

suspending a powder including the polypeptide and one or more of a matrix polymer, a carboxylate salt, and a cellulose in a polar liquid;
filtering the suspension to yield a target filtrate;
purifying the target filtrate by one or more of tangential flow filtration, size exclusion chromatography, reverse phase liquid chromatography, or combinations thereof;
and
collecting the purified polypeptide.

2 more elements

Dependencies are inferred from the claim text.

C07K 1/34
Extraction; Separation; Purification: by filtration, ultrafiltration or reverse osmosis
B01D 15/166
Relating to the conditioning of the fluid carrier: fluid composition conditioning, e.g. gradient
B01D 15/325
Bonded phase chromatography: reversed phase
B01D 15/34
Characterised by the separation mechanism: size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation

From the US filing history. Foreign family members aren’t listed.

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