Compositions and methods related to tumor activated antibodies targeting psma and effector cell antigens
AssigneeJanux Therapeutics, Inc.
InventorsDavid CAMPBELL, Byron ROBINSON, Zachariah Augustus MCIVER
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Abstract
Described herein are compositions and formulations comprising a recombinant polypeptide. Related methods and uses of these compositions and formulations are also described herein.
Claims214
A method for treating cancer comprising administering to a subject in need thereof a first dose and a target dose of an isolated recombinant polypeptide complex, wherein the first dose is at least about 100 μg and the target dose is higher than the first dose, and wherein the isolated recombinant polypeptide complex comprises a first chain with an amino acid sequence having at least 80% sequence identity to SEQ ID NO:
- 1 and a second chain with an amino acid sequence having at least 80% sequence identity to SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.