Reciprocating pump segment

An infusion set for loading into an infusion pump, comprising:

• a pumping segment comprising:
• a compressible tubing segment;
• and
• two support keys, fixed on opposing ends of the compressible tubing segment,
• wherein the two support keys comprises at least one gear,
• wherein the pumping segment is configured to be loaded into an infusion pump comprising one or more corresponding gears configure to, when the pumping segment is loaded into the infusion pump, interface with the at least one gear of the two support keys and configured to at least partially rotate the pumping segment about a central axis of the pumping segment by causing the at least one gear of the two support keys to at least partially rotate,
• wherein, when the pumping segment is loaded into the infusion pump, the pumping segment is constrained in a predetermined linear position between a rigid tubing support surface and a pumping mechanism of the infusion pump, while the pumping mechanism applies a periodic compression force to the compressible tubing segment of the pumping segment.

An method of operating a rotating infusion set in an infusion pump, comprising:

• receiving a pumping segment into the infusion pump, the pumping segment comprising a compressible tubing segment constrained by two support keys, fixed on opposing ends of the compressible tubing segment;
• receiving the two support keys into corresponding keyways of two rotating members of the infusion pump;
• and
• causing each rotating member to at least partially rotate the pumping segment about a central axis of the pumping segment by causing the one or more respective support keys to at least partially rotate, while constraining the pumping segment in a predetermined linear position between a rigid tubing support surface and a pumping mechanism of the infusion pump and while the pumping mechanism applies a periodic compression force to the pumping segment.