Malaria immunogen and methods of using same
AssigneeUNM Rainforest Innovations
InventorsBryce C. CHACKERIAN, Alexandra FRANCIAN
Life of this patent
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Abstract
An immunogen generally includes an immunogenic carrier that includes a virus-like particle (VLP) and an antigenic Anopheles spp. TRIO peptide that includes amino acids VDDLMAKFN (SEQ ID NO:1) or AANLRDKFN (SEQ ID NO:5) linked to the immunogenic carrier. The immunogen can be formulated into a composition such as vaccine. The composition or vaccine may be used to treat a subject having, or at risk of having malaria. The composition or vaccine may be used to treat a subject having Plasmodium falciparum blood stage parasitemia.
Claims25
An immunogen comprising:
- an immunogenic carrier comprising a Qβ bacteriophage virus-like particle (VLP);
- and
- an antigenic Anopheles spp. TRIO peptide linked to the immunogenic carrier.
A method of treating malaria in an individual, the method comprising administering a therapeutically effective amount of a composition to the individual, the composition comprising an immunogen, the immunogen comprising:
- an immunogenic carrier;
- and
- an antigenic Anopheles spp. TRIO peptide linked to the immunogenic carrier.
25-34. (canceled)
Dependencies are inferred from the claim text.