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AssigneeProThera Biologics, Inc.
InventorsYow-Pin LIM, Denice SPERO, Andre Richard SANTOSO
Estimating the term…
Featured are a foodstuff containing an inter-alpha inhibitor protein (IαIp) (e.g., IαI, PαI, a heavy chain (e.g., H1, H2, H3, H4, and/or H5), a light chain (e.g., bikunin), or a combination thereof), methods of preparing a foodstuff containing an IαIp, and methods of treating and/or reducing the likelihood of developing disease or condition (e.g., a disease or condition characterized by inflammation and/or low levels of an IαIp) in a subject in need thereof by administering a composition or a foodstuff containing an IαIp. Also featured are methods of purifying an IαIp (e.g., IαI, PαI, a heavy chain (e.g., H1, H2, H3, H4, and/or H5), a light chain (e.g., bikunin), or a combination thereof) from milk.
A foodstuff comprising an inter-alpha inhibitor protein (IαIp), wherein the IαIp is present in the foodstuff in an amount of at least about 0.01 milligram per mg of the foodstuff.
A method of treating, reducing the symptoms of, inhibiting progression of, or reducing the likelihood of developing a disease or condition in a subject comprising administering to the subject a foodstuff comprising a therapeutically effective amount of an IαIp.
A method of purifying an IαIp comprising:
A method of purifying an IαIp comprising:
A method of making a composition for oral consumption comprising admixing an IαIp with a foodstuff.
A kit comprising a composition comprising an IαIp, a foodstuff, instructions for admixing the composition with the foodstuff, and, optionally, instructions for therapeutic use.
A method of treating, reducing the symptoms of, inhibiting progression of, or reducing the likelihood of developing necrotizing enterocolitis in a subject in need thereof comprising administering to the subject a composition comprising in admixture a therapeutically effective amount of an IαIp.
Dependencies are inferred from the claim text.