Multi-sensor patch and signal analyzer that enable safe cardiac ablation

A system for delivering pulsed field ablation comprising:

• an ablation catheter comprising one or more electrodes;
• a patch configured for placement on a body of a patient, the patch comprising a plurality of sensors and one or more return electrodes thereon, wherein the plurality of sensors comprises one or more electrocardiogram (ECG) electrodes and one or more photoplethysmogram (PPG) sensors;
• a pulse generator configured to generate electrical pulses for delivery from the one or more electrodes of the ablation catheter;
• and
• a processor configured to analyze data received from the plurality of sensors, and based on the analyzed data, identify a portion of a cardiac cycle of the patient in which to deliver the electrical pulses, and trigger the pulse generator to generate the electrical pulses during the identified portion.

A system for delivering pulsed field ablation comprising:

• an ablation catheter comprising one or more electrodes;
• a patch configured for placement on a body of a patient, the patch comprising a plurality of sensors and four return electrodes thereon, wherein the plurality of sensors comprises four electrocardiogram (ECG) electrodes and three photoplethysmogram (PPG) sensors;
• a pulse generator configured to generate electrical pulses for delivery from the one or more electrodes of the ablation catheter;
• and
• a processor configured to analyze data received from the plurality of sensors, and based on the analyzed data, enable generation of the electrical pulses by the system.