Device and Method for Analyte Isolation

A device for isolating a target analyte from a sample, the device comprising:

• an adaptor configured for mutually exclusively engaging with a first compartment and a second compartment, and the adaptor comprising a cap having a hole and a bead capture plunger,
• a magnetic housing and plunger comprising a magnet,
• wherein the bead capture plunger is a hollow elongated structure that is inserted into the first or the second compartment when the adaptor engages with the first or second compartment, and wherein the bead capture plunger also provides space for engaging with the magnet of the magnetic housing and plunger,
• wherein the magnet of the magnetic housing and plunger captures magnetic particles that may be present in the first compartment or in the second compartment,
• and wherein moving the adaptor from the first compartment to second compartment causes a sealed gas-phase transfer of magnetic particles from the first compartment to the second compartment.

A device for isolating a target analyte from a sample, the device comprising:

• an adaptor configured for engaging with a first compartment and a second compartment, wherein the first compartment is cylindrical tube and the second compartment is below the first compartment and is sealingly connected to the first compartment,
• the adaptor comprising a bead capture plunger, wherein the bead capture plunger passes through the center of the first compartment and comprises a hollow longitudinal center that provides a space for accommodating a magnet from a magnet housing and plunger, and wherein the bead capture plunger comprises a bead capture area,
• wherein the magnet housing and the plunger is configured to pass through the bead capture plunger and capture magnetic particles that may be present in the first compartment in the bead capture area of the bead capture plunger, and
• the magnetic housing and plunger further configured to piercably move from the first compartment into the sealingly connected second compartment thereby causing a sealed gas-phase transfer of magnetic particles from the first compartment to the second compartment.