Antibacterial wound treatments with clot-promoting properties
AssigneeUniversity of Georgia Research Foundation, Inc.
InventorsJitendra PANT, Dieu Thao NGUYEN, Hitesh Handa
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Abstract
Wound dressings and methods for treating a wound are provided. The wound dressing can have an environment-facing side that includes a biocompatible material having a polymer crosslinked with an antimicrobial effective amount of a NO-donor and a wound-facing side including a biocompatible resinous matrix and an antifibrinolytic agent. The wound dressing can promote fibrin formation and rapid platelet aggregation, and has antimicrobial properties. The dressing can be applied directly to the wound.
Claims7
A wound dressing comprising a biocompatible material comprising a polymer and an antimicrobial effective amount of a NO-donor, wherein the NO-donor consists of S-nitroso-N-acetylpenicillamine, S-nitrosocysteamine, S-nitrosocysteine, S-nitroso-N-acetyl cysteamine, S-nitroso-N-acetyl cysteine, S-nitrosothioglycolate methyl S-nitrosothioglycolate, S-nitrosoglutathione, sodium nitroprusside, or any combination thereof.
Dependencies are inferred from the claim text.