Polymeric material and preparation method thereof, and drug-loading material

A method for preparing a polymeric material, comprising:

• mixing a crosslinking precursor, a crosslinking agent, and polyelectrolytes;
• and
• performing a crosslinking polymerization reaction under an external condition stimulation to form the polymeric material, wherein polymeric material comprises:
• a crosslinked polymer, and a plurality of the polyelectrolytes grafted via chemical bonds onto a three-dimensional network structure of the crosslinked polymer, wherein each of the polyelectrolytes comprises a plurality of ionizable groups, so that the ionizable groups form a local potential after ionization to induce aggregation of particles having an opposite electric charge.

A drug-loading material, comprising:

• a polymeric material, comprising:
• a crosslinked polymer, and a plurality of polyions grafted by chemical bonds onto a three-dimensional network structure of the crosslinked polymer;
• and
• a plurality of drug particles, adsorbed onto the polymeric material through electrostatic interaction, wherein
• each of the polyions comprises a plurality of charged groups, and the plurality of charged groups forms a local potential to induce aggregation of the drug particles having opposite electric charges.