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US 2026/0124233 A1Published application
Compositions for aquaculturing
AssigneeViAqua Therapeutics Ltd.
InventorsShai UFAZ, Ami SCHLESINGER, Ori KOSHET, Margarita KANTEEV
Life of this patent
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Abstract
Particulate compositions comprising low molecular weight chitosan and ss or dsRNA partially complementary to, binding to or at least 90% identical to mRNA targets of viruses pathogenic in farmed crustaceans, compositions and farmed aquatic crustaceans comprising the same, and methods for their use in treating or preventing viral infection in aquaculture are provided.
Claims18
A particulate composition comprising:
- particles comprising chitosan and at least one type of RNA molecule comprising a nucleic acid sequence at least 50 bases in length,
- wherein said chitosan is 50-100% deacetylated low molecular weight chitosan, wherein the molecular weight of said chitosan is in the range of 5-100 kDa, wherein the chitosan:RNA mass ratio (w/w) of the particles is in the range of 0.3-0.9, wherein said RNA molecule is capable of silencing expression of a gene when administered to an organism expressing said gene, and wherein the particulate composition comprises >50% particles in the range of 10-300 μm.
Dependencies are inferred from the claim text.