Polypeptide formulations for oral delivery
AssigneeBhami's Research Laboratory, Pvt. Ltd.
InventorsBhami Shenoy, Suryakanth Motilal Pai
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Abstract
The present disclosure provides, among other things, methods and compositions for the oral administration of polypeptides. Many polypeptides are typically administered in liquid solutions by intravenous or subcutaneous injection. The present disclosure provides methods and compositions that include a polypeptide formulation, e.g., truffle, tablet, globule, candy, capsule formulation suitable for oral administration, where the formulation includes an amorphous polypeptide composition or a crystallized polypeptide composition and a pharmaceutically acceptable carrier.
Claims38
A polypeptide formulation for oral delivery comprising:
- (1) a carrier polypeptide composition;
- (2) an active polypeptide composition;
- and optionally (3) a pharmaceutically acceptable carrier.
The polypeptide formulation or method of any one of claims 1-34, wherein the polypeptide formulation is formulated for delivery to the gut, optionally wherein the polypeptide formulation is formulated for delivery to stomach and/or intestine.
Dependencies are inferred from the claim text.