Anti-respiratory syncytial virus antibody and related use thereof

An anti-respiratory syncytial virus (RSV) monoclonal antibody or an antigen-binding fragment thereof, comprising a heavy-chain variable region and a light-chain variable region, wherein:

• 1) the heavy-chain variable region comprises heavy-chain complementarity-determining regions VH CDR1, VH CDR2 and VH CDR3 with amino acid sequences shown in SEQ ID NO:
• 1-3, respectively, and the light-chain variable region comprises light-chain complementarity-determining regions VL CDR1, VL CDR2 and VL CDR3 with amino acid sequences shown in SEQ ID NO:
• 4-6, respectively, wherein the sequence shown in SEQ ID NO:
• 6 is QQYSNFPXT, wherein X is C or F;
• 2) the heavy-chain variable region comprises heavy-chain complementarity-determining regions VH CDR1, VH CDR2 and VH CDR3 with amino acid sequences shown in SEQ ID NO:
• 7-9, respectively, and the light-chain variable region comprises light-chain complementarity-determining regions VL CDR1, VL CDR2 and VL CDR3 with amino acid sequences shown in SEQ ID NO:
• 10-12, respectively;
• or
• 3) the heavy-chain variable region comprises heavy-chain complementarity-determining regions VH CDR1, VH CDR2 and VH CDR3 with amino acid sequences shown in SEQ ID NO:
• 13-15, respectively, and the light-chain variable region comprises light-chain complementarity-determining regions VL CDR1, VL CDR2 and VL CDR3 with amino acid sequences shown in SEQ ID NO:
• 16-18, respectively.