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US 2026/0116902 A1Published application
Novel compound as functional antagonist for s1pr1 and s1pr4
AssigneeNextgen Bioscience Co., Ltd.
InventorsBongyong LEE, Yanghae Park, Eunjeong Kim, Hojung Choi
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Abstract
The present invention relates to a novel compound acting as a functional antagonist for S1PR1 and S1PR4, and a use thereof. The compound according to the present invention exhibits significantly excellent binding strength to S1PR1 and S1PR4 receptors, thus exhibiting an excellent effect in preventing or treating inflammatory bowel disease, alopecia areata (AA), or an autoimmune disease.
Claims17
A compound represented by Formula 1 below or a pharmaceutically acceptable salt thereof:
- wherein R is C1-15 alkyl.
An S1PR1 and S1PR4 antagonist represented by Formula 1 below:
- wherein R is C1-15 alkyl.
Dependencies are inferred from the claim text.