Calsequestrin-based metal ion reactive particle and uses thereof
AssigneeToolBio. Co
InventorsSe Ho PARK, Sung Hyun KIM
Life of this patent
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Abstract
The present invention relates to calsequestrin-based metal ion reactive particles and their applications. More specifically, the invention concerns calsequestrin-based metal ion reactive particles, which are prepared by combining bioactive substances frequently used in pharmaceuticals and cosmetics with calsequestrin (CSQ) and then reacting them with metal ions. This invention also relates to the use of these particles as drug delivery carriers, pharmaceutical compositions, or vaccines. The metal ion reactive particles according to the present invention can enhance the in vivo and in vitro stability of bioactive substances, prolong their active duration, increase their half-life in the body, and improve antigen delivery efficiency.
Claims21
-69. (canceled)
A particle containing:
- calsequestrin (CSQ);
- a bioactive substance linked to the CSQ;
- and
- a metal ionically linked to CSQ.
Dependencies are inferred from the claim text.