Endoscopic systems and methods for duodenal mucosal reshaping and resurfacing
AssigneeEndolastic, Inc.
InventorsFrederick Haller, Paul Robertson
Life of this patent
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Abstract
Non-resective endoscopic systems and methods for altering gastrointestinal organs to treat Type 2 Diabetes Mellitus (T2DM). The non-resective endoscopic systems and methods provide improved tissue capture to create localized pressure necrosis to target tissue areas. The non-resective endoscopic systems and methods include banding target tissue areas utilizing a ligation band. The ligation band creates a uniform distribution of pressure to improve tissue retention and pressure necrosis for eliciting a healing response.
Claims15
An endoscopic system for duodenal mucosal resurfacing, the endoscopic system comprising:
- an endoscope including at least one end barrel;
- and
- at least one ligation band;
- wherein the endoscope is operable to capture tissue corresponding to a patient,
- wherein the captured tissue includes a mucosal layer;
- and
- wherein the at least one ligation band is operable to band the mucosal layer;
- and
- wherein, once the mucosal layer is banded, the at least one ligation band generates pressure across the banded tissue, wherein the banded tissue undergoes pressure necrosis to elicit a healing response.
A method for treating Type 2 Diabetes Mellitus comprising:
- identifying at least one target area in a duodenum of a patient;
- capturing, via an endoscopic device, the at least one target area;
- deploying at least one elastomeric ligation band to a portion of the at least one target area;
- and
- banding, via the at least one elastomeric ligation band, the portion of the at least one target area, wherein the at least one target area undergoes pressure necrosis to elicit a healing response, wherein the healing response includes tissue regeneration of the duodenal tissue to improve insulin sensitivity.
A method of modifying duodenal mucosal tissue to treat Type 2 Diabetes Mellitus comprising:
- inserting an endoscopic device into a duodenum corresponding to a patient;
- identifying at least one target area for tissue modification;
- capturing, via the endoscopic device, at least a portion of the at least one target area of the duodenum;
- deploying at least one elastomeric ligation band to the portion of the at least one target area;
- and
- banding, via the at least one elastomeric ligation band, the portion of the at least one target area;
- wherein the at least one target area undergoes pressure necrosis to elicit a natural healing response, wherein, as a result of the banding, tissue sloughs off the at least one target area, wherein the healing response includes tissue regeneration to improve insulin sensitivity and glucose metabolism.
Dependencies are inferred from the claim text.