Harmonization of diffusion magnetic resonance imaging

A non-transitory computer-readable storage medium for use in conjunction with a computer system, the computer-readable storage medium configured to store program instructions that, when executed by the computer system, causes the computer system to perform one or more operations comprising:

• receiving information specifying magnetic-resonance diffusion measurements, wherein the magnetic-resonance diffusion measurements are associated with at least an individual and a first site;
• performing pairwise harmonizing of the magnetic-resonance diffusion measurements based at least in part on target magnetic-resonance diffusion measurements, wherein the target magnetic-resonance diffusion measurements are associated with a population and one or more target sites, and
• wherein the magnetic-resonance diffusion measurements and the target magnetic-resonance diffusion measurements are acquired using different magnetic-resonance scanners;
• and
• performing quality control on the pairwise harmonized magnetic-resonance diffusion measurements, wherein the quality control comprises comparing the pairwise harmonized magnetic-resonance diffusion measurements associated with the first site and the one or more target sites, wherein the target magnetic-resonance diffusion measurements from the population are used as a prior for computing of parameters for a moving population associated with the first site.

A method for performing pairwise harmonization, comprising:

• by a computer system:
• receiving information specifying magnetic-resonance diffusion measurements, wherein the magnetic-resonance diffusion measurements are associated with at least an individual and a first site;
• performing the pairwise harmonizing of the magnetic-resonance diffusion measurements based at least in part on target magnetic-resonance diffusion measurements, wherein the target magnetic-resonance diffusion measurements are associated with a population and one or more target sites, and
• wherein the magnetic-resonance diffusion measurements and the target magnetic-resonance diffusion measurements are acquired using different magnetic-resonance scanners;
• and
• performing quality control on the pairwise harmonized magnetic-resonance diffusion measurements, wherein the quality control comprises comparing the pairwise harmonized magnetic-resonance diffusion measurements associated with the first site and the one or more target sites, wherein the target magnetic-resonance diffusion measurements from the population are used as a prior for computing of parameters for a moving population associated with the first site.