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US 2026/0109954 A1Published application
Systems and Methods to Protect Biological Cells
AssigneeMembrane Protective Technologies, Inc.
InventorsLisa A. Herickhoff, Myles Shepherd
Life of this patent
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Abstract
Embodiments of the present invention may provide protecting, preserving, and even repairing biological cells during in vitro processing. A uniform environment such as a protective layer with exogeneous lipids may be formed around biological cells which may interact with the plasma membranes of the cells.
Claims21
A method of processing biological cells comprising the steps of:
- providing a biological cell;
- adding exogeneous lipids to said biological cell before, during, or after in vitro processing of said biological cell;
- forming a protective layer around at least part of said biological cell with said exogeneous lipids to create a stabilized biological cell;
- in vitro processing said stabilized biological cell;
- and
- substantially preserving a plasma membrane of said biological cell during said in vitro processing.
3 more elements
A method of processing biological cells comprising the steps of:
- providing a biological cell;
- adding exogeneous lipids to said biological cell;
- forming a protective layer around at least part of said biological cell with said exogeneous lipids;
- in vitro processing said biological cell;
- and
- substantially preserving a polarized state of said biological cell during in vitro processing with said protective layer.
3 more elements
A method of processing biological cells comprising the steps of:
- providing a biological cell having an intrinsic curvature of its plasma membrane;
- adding exogeneous lipids to said biological cell before, during, or after in vitro processing of said biological cell;
- forming a protective layer mimicking said intrinsic curvature around at least part of said plasma membrane with said exogeneous lipids to create a membrane-stabilized biological cell;
- in vitro processing said membrane-stabilized biological cell;
- and
- substantially preserving said plasma membrane of said biological cell during said in vitro processing.
3 more elements
A method of restoring damaged cell membranes comprising the steps of:
- providing a damaged plasma membrane of a biological cell;
- adding exogenous lipids to said damaged plasma membrane of said biological cell;
- forming a protective layer over at least part of said damaged plasma membrane of said biological cell with said exogenous lipids;
- allowing said exogenous lipids to interact with said damaged plasma membrane of said biological cell;
- and
- repairing said damaged plasma membrane from said interactions of said exogenous lipids with said damaged plasma membrane.
3 more elements
21-49. (canceled)
Dependencies are inferred from the claim text.