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US 2026/0109863 A1Published application
Azasilane detectable compounds
AssigneeSingular Genomics Systems, Inc.
InventorsMegha CILA, Ronald GRAHAM, Rodrigo RODRIGUEZ
Life of this patent
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Abstract
Disclosed herein, inter alia, are silicon containing detectable compounds and methods of use thereof.
Claims20
A compound having the formula:
- wherein
- R1 and R8 are each independently -L1-R13, hydrogen, —OH, —NH2, —COOH,
- —CONH2, —NO2, —SH, —SO3H, —SO4H, —PO3H, or substituted or unsubstituted heteroalkyl;
- R9, R10, R11, and R12 are each independently -L1-R13, hydrogen,
- halogen, —OH, —NH2, —COOH, —CONH2, —NO2, —SH, —SO3H, —SO4H, —PO3H, substituted or unsubstituted alkyl, or substituted or unsubstituted heteroalkyl;
- R2 and R3 are each independently -L1-R13, substituted or unsubstituted alkyl, or substituted or unsubstituted heteroalkyl;
- wherein no more than one of R1, R2, R3, R8, R9, R10, R11, and R12 is -L1-R13;
- Ring A and Ring B are each independently a heterocycloalkyl;
- R34 and R36 are each independently halogen, —OH, —NH2, —COOH, —SO3H,
- —SO4H, —SO2NH2, —PO4H, —PO3H, unsubstituted alkyl, unsubstituted heteroalkyl, unsubstituted cycloalkyl, unsubstituted heterocycloalkyl, unsubstituted aryl, or unsubstituted heteroaryl;
- z34 and z36 are independently an integer from 0 to 6;
- R13 is a biomolecule;
- and
- L1 is a covalent linker or a bond.
11 more elements
Dependencies are inferred from the claim text.